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Nicholas Holmes, M.D.

Business Address:
7930 Frost Street, Suite 300
San Diego, CA 92123
Tel: (858) 279-8527

Education

Undergraduate: Georgetown University
College of Arts and Sciences
B.S. Biology, Pre-Med 1985-1989

Medical School: Georgetown University
School of Medicine
M.D. 1989-1993

Graduate School:
Johns Hopkins University
School of Professional Studies in Business Education
Business of Medicine Graduate Certificate Program
September 2002-June 2003

Military Course Training

Officer Indoctrination School
U.S. Naval Base Newport
Newport, RI
June 1990-August 1990

Combat, Casualty and Care Course (C4)
Ft. Sam Houston
San Antonio, TX
March 1994

Department Head Fundamentals Course
Naval Medical Center San Diego
June 1999

Intermediate Officer Leadership Training Course
Navy Leadership Training Unit
Coronado, CA
July 2001

Basic Medical Officers Course
Navy e-Learning/Navy Knowledge On-line
Nov 2005

Professional Training and Experience

Internship: Basic Surgery Internship
  Naval Medical Center San Diego
  San Diego, CA
  June 1993-June 1994

Residency: Urology
  Naval Medical Center San Diego
  San Diego, CA
  June 1994-June1999

Fellowship: Pediatric Urology
  University of California San Francisco
  San Francisco, CA
  July 1999-July 2001

Academic Appointments

Clinical Instructor
Department of Urology
University of California San Francisco
July 1999 to July 2001

Assistant Residency Program Director
Department of Urology
National Naval Medical Center
Bethesda, MD
March 2002 to July 2002

Assistant Professor of Surgery
Department of Surgery
F. Edward Hébert School of Medicine
Uniformed Services University of Health Sciences
Bethesda, MD
May 2002 to present

Work History/Military Assignment History

Job Title: Surgery Intern
Duty Location: Naval Medical Center San Diego
Dates of Assignment: June 1993-June 1994

Job Title: Urology Resident
Duty Location: Naval Medical Center San Diego
Dates of Assignment: June 1994-June 1999

Work History/Military Assignment History
Job Title: Fellow, Pediatric Urology/Full-time Out-service Training (FTOS)
Duty Location: University of California San Francisco
Dates of Assignment: July 1999-July 2001

Job Title: Head, Pediatric Urology
Duty Location: National Naval Medical Center Bethesda
Dates of Assignment: August 2001-August 2004

Job Title: Head, Pediatric Urology
Duty Location: Naval Medical Center San Diego
Dates of Assignment: September 2004-May 2007

Job Title: Medical Corps Specialty Leader for Urology to the Chief,
Bureau of Medicine and Surgery, U.S. Navy
Dates of Appointment: March 2004-March 2007

Job Title: Chairman, Department of Urology
Duty Location: Naval Medical Center San Diego
Dates of Appointment: July 2005-May 2007

Job Title: Director, Division of Pediatric Urology
Location: Children's Specialist San Diego/Rady Children's Hospital
Dates of Appointment: July 2007

Licensure and Certification

Diplomat of the National Board of Medical Examiners
      Certified 01 July 1994

Current Unrestricted California Medical State License

State of California Fluoroscopy X-ray Supervisor & Operator

Diplomat of the American Board of Urology
      Certified 22 February 2003

Honors and Recognition

William C. Maxted Award
Outstanding Academic Performance in Urology
Georgetown University, School of Medicine
1993

Surgery Intern of the Year Award
Naval Medical Center San Diego
1993-1994

Trauma Surgery Intern of the Year Award
Mercy Hospital
San Diego, CA
1993-1994

Frank Hinman, Jr. Award
Best Clinical Research Paper
"Fetal Intervention for Posterior Urethral Valves: Long-term Postnatal Outcomes"
Society of Pediatric Urology
Atlanta, GA
April 29,2000

Clinical Research Prize Finalist
"Defects in Androgen Production as a Role in Etiology of Hypospadias"
American Academy of Pediatrics, Section on Urology
National Convention and Exhibition
San Francisco, CA
October 2001

Navy and Marine Corps Achievement Medal
26 August 2002

Navy and Marine Corps Commendation Medal
30 July 2004

Professional Societies

  • American Urologic Association
  • Society of Government Service Urologist
  • Society of Fetal Urology
  • American Association of Pediatric Urology

Presentations

The 44th Annual James E. Kimbrough Urological Seminar
Society of Government Service Urologist
Podium Presentations
Phoenix, AZ December 1996
"Renal Imaging with Spiral CT Scan: Clinical Applications"

Annual Resident Research Competition March 1997
Clinical Investigation Department
Naval Medical Center San Diego
"Preoperative Radiotherapy for Carcinoma of the Urinary Bladder; Time for Reappraisal"

Western Section American Urological Association, Inc.
73rd Annual Meeting, Salt Lake City, UT September 1997
Poster Session
"Preoperative Radiotherapy for Carcinoma of the Urinary Bladder; Time for Reappraisal"
"Testicular Infarction: Unusual Presentation of Sickle Cell Disease"
"A Pediatric Case of Distal Ureteral Intussusception Secondary to a Fibroepithelial Polyp without Hydronephrosis"

The 45th Annual James E. Kimbrough Urological Seminar
Society of Government Service Urologist
Podium Presentations
San Francisco, CA November 1997
"Preoperative Radiotherapy for Carcinoma of the Urinary Bladder; Time for Reappraisal"
"Testicular Infarction: Unusual Presentation of Sickle Cell Disease"

Northern California Pediatric Nephrology Seminar
San Francisco, CA October 1999
"Genetics of Vesicoureteral Reflux"

The Society of Pediatric Urology
Podium Presentation
Atlanta, GA April 2000
"Fetal Intervention for Posterior Urethral Valves: Long-term Postnatal Outcomes"

Annual UCSF Pediatric Urology Seminar
San Francisco, CA February 2000
"Endoscopic Incision of Prenatally Diagnosed Ureteroceles"

American Academy of Pediatrics-Section of Urology and European Society for Paediatric Urology
Joint Meeting June 2000
Tours, France
Poster Session
"Adrenal Cortical Carcinoma in Children: UCSF Patient Experience"
Podium Presentations:
"Placement of Artificial Urinary Sphincter in Children and Simultaneous Gastrocystoplasty"
"Prenatal Diagnosis of Ureteroceles with Early Neonatal Endoscopic Puncture Reduces Postnatal Urinary Tract Infection"

The Society of Fetal Urology Biannual Meeting
Chicago, IL October 2000
Podium Presentation
"Fetal Intervention for Myelomeningocele: Effect on Post-natal Bladder Function"

Western Section American Urological Association, Inc.
76th Annual Meeting, Palm Springs, CA November 2000
Round-Table Presentation
"Heterotopic Bone Formation in a Pediatric Patient"

The 48th Annual James E. Kimbrough Urological Seminar
Society of Government Service Urologist
San Diego, CA January 2001
Poster Presentation
"Adrenal Cortical Carcinoma in Children: UCSF Patient Experience"
Podium Presentations
"Fetal Intervention for Posterior Urethral Valves: Long-term Post-natal Outcomes"
"Use of Endoscopic Puncture of Ureteroceles in the Newborn Period to Reduce the Incidence of Urosepsis"

Annual UCSF Pediatric Urology Seminar
San Francisco, CA March 2001
"Hypercalciuria and UTI: The Missing Link in a Negative Radiologic Work-up"

The Society of Pediatric Urology
Podium Presentation
Anaheim, CA May 2001
"Patterns of Dysfunctional Voiding with Ureterocele Complex"

American Academy of Pediatrics, Section on Urology
National Convention and Exhibition
Podium Presentation
San Francisco, CA October 2001
"Defects in Androgen Production as a Role in Etiology of Hypospadias"

The Society of Pediatric Urology
Podium Presentation
Orlando, FL May 2002
"Hypercalciuria and UTI: The Missing Link in a Negative Radiologic Work-up"

Annual UCSF Pediatric Urology Seminar
San Francisco, CA February 2002
"Behavioral Modifications in Voiding Dysfunction"

Annual UCSF Pediatric Urology Seminar
San Francisco, CA October 2004
"Update on the use of DDAVP"

The Society of Fetal Urology Biannual Meeting
Washington, D.C. October 2005
Podium Presentation
"Pre-natal Diagnosis of Megacystitis-Microcolon-Intestinal Hypoperistalsis Syndrome"

The 53rd Annual James E. Kimbrough Urological Seminar
Society of Government Service Urologist
Savannah, GA January 2006
Podium Presentation
"Pre-natal Diagnosis of Megacystitis-Microcolon-Intestinal Hypoperistalsis Syndrome"
State-of-the-Art Lecture
"Hypospadias: The Evaluation and Treatment of the Megameatus"

Research

Clinical Investigation Department-Research Protocol August 1996
Naval Medical Center San Diego
S96-035 "Preoperative Short Course Radiotherapy for Carcinoma of the Urinary Bladder Confers Local Control Benefit"

Clinical Investigation Department-Research Protocol October 1996
Naval Medical Center San Diego
S96-0117 "Visualization of the Paratesticular Lymphatic Tissue in the Canine Model"

Committee on Human Research-Research Protocol December 1999
University of California San Francisco
H7378-16951-01A "Defects in Androgen Production as a Role in Etiology of Hypospadias"

Committee on Animal Research-Research Protocol March 2000
University of California San Francisco
"Pharmacologic Induction of Hypospadias in the Mouse Model via Manipulation of In Utero Androgen Exposure"

Publications

Holmes, N. M.: Prenatal diagnosis of Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome. Dialogues Pediatric Urology (accepted for publication December 2005).

Holmes, N.M. and Hinds, A.: Chapter 6-Urinary Tract Infection in Children. Handbook of Pediatric Urology, Editors Baskin and Kogan. 2nd Edition. Lippincott Williams & Wilkins, 2005.

Holmes, N.M., Miller, W., and Baskin, L.S.: Lack of defects in Androgen Production in Children with Hypospadias. Journal of Clinical Endocrinology and Metabolism 89(6): 2811-2816, June 2004.

Smith, K.E., Holmes, N. M., Lieb, J.L., Mandell, J., Baskin, L.B., and Kogan, B.A.: Stented vs. Non-stented pediatric pyeloplasties: A Modern Series and Review of the Literature. Journal of Urology 168: 1127-1130, September 2002.

Holmes, N.M., Coplen, D.E., Strand, W., Husmann, D., and Baskin, L.: Is Bladder Dysfunction and Incontinence Associated with Ureteroceles: Congenital or Acquired? Journal of Urology 168: 718-719,
August 2002.

Holmes, N.M., Nguyen, H., and Baskin, L.S.: Fetal Intervention for Myelomeningocele: Effect on Post-natal Bladder Function. Journal of Urology (166): 2383-2386, December 2001.

Holmes, N.M., and Baskin, L.S.: Heterotopic Bone Formation in a Pediatric Patient. Journal of Urology 166: 1859, November 2001.

Holmes, N.M., Kogan, B.A. and Baskin, L.B.: Placement of Artificial Urinary Sphincter in Children and Simultaneous Gastrocystoplasty. Journal of Urology 165: 2366-2368, June 2001.

Holmes, N.M., Harrison, M., and Baskin, L.B.: Fetal Surgery for Posterior Urethral Valves: Long-term Outcomes. Pediatrics 108 (1): 1-7, July 2001 (http://www.pediatrics.org/cgi/content/full/108/1/e7).

Cilento, B.G., Holmes, N.M. and Canning, D.A.: Plastibellâ Complications Revisited. Clinical Pediatrics 38: 239-242, April 1999.

Holmes, N.M., and Kane, C.J.: Testicular Infarction Associated with Sickle Cell Disease. Journal of Urology 160: 130, July 1998.

Holmes, N.M., Kane, C.J., and Cilento, B.G.: Renal Tubular Acidosis.  Urology 50 (2): 279, August 1997.

Holmes, N.M., McBroom, S., Puckett, M.L., and Kane C.J.: Renal Imaging with Spiral CT Scan: Clinical Applications.  Techniques in Urology (3) 4: 202-208, Winter 1997.

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